Explore our research fingerprint
Jump over to the division’s research profile to fully explore the nature and scope of our research publications over the years.
Our labs
Horani Lab
Amjad Horani, MD
The Horani lab research focuses on airway epithelial cell differentiation and regulation with special interest in cilia assembly and how it relates to impaired mucociliary clearance and the biology of primary ciliary dyskinesia. The lab uses primary culture of human and mouse cells and employs genetic manipulation methods to investigate the function of novel proteins involved in ciliogenesis.
Rubenstein Lab
Ronald Rubenstein, MD, PhD
The Rubenstein lab focuses on the mechanisms by which small molecules may improve the function of mutant proteins that cause disease due to abnormal biogenesis and trafficking. These studies initially focused on epithelial ion channels relevant to Cystic Fibrosis, and have expanded to address fundamental biologic questions related to the regulation of protein biogenesis and trafficking in a number of other diseases and conditions.
Recent publications
- Host factors are associated with vaginal microbiome structure in pregnancy in the ECHO Cohort ConsortiumMcKee, K., Bassis, C. M., Golob, J., Palazzolo, B., Sen, A., Comstock, S. S., Rosas-Salazar, C., Stanford, J. B., O’Connor, T., Gern, J. E., Paneth, N., Dunlop, A. L., Smith, P. B., Newby, L. K., Adair, L., Jacobson, L. P., Catellier, D., McGrath, M., Douglas, C. & Duggal, P. & 271 others, Knapp, E., Kress, A., Blackwell, C. K., Mansolf, M. A., Lai, J. S., Ho, E., Cella, D., Gershon, R., Macy, M. L., Das, S. R., Freedman, J. E., Mallal, S. A., McLean, J. A., […]
- Apnea, Intermittent Hypoxemia, and Bradycardia Events Predict Late-Onset Sepsis in Infants Born Extremely PretermThe Prematurity-Related Ventilatory Control (Pre-Vent) Investigators, Aug 2024, In: Journal of Pediatrics. 271, 114042.Research output: Contribution to journal › Article › peer-review
- Research protocol and recruitment redesign of a study of pregnant women and their infants during the COVID-19 pandemic: Childhood Allergy and the NeOnatal Environment (CANOE)ECHO Children's Respiratory and Environmental Workgroup, Aug 2024, In: Journal of Allergy and Clinical Immunology: Global. 3, 3, 100270.Research output: Contribution to journal › Article › peer-review
- COVID-19 Vaccination in Patients with Inborn Errors of Immunity Reduces Hospitalization and Critical Care Needs Related to COVID-19: a USIDNET ReportMcDonnell, J., Cousins, K., Younger, M. E. M., Lane, A., Abolhassani, H., Abraham, R. S., Al-Tamemi, S., Aldave-Becerra, J. C., Al-Faris, E. H., Alfaro-Murillo, A., AlKhater, S. A., Alsaati, N., Doss, A. M. A., Anderson, M., Angarola, E., Ariue, B., Arnold, D. E., Assa’ad, A. H., Aytekin, C. & Bank, M. & 138 others, Bergerson, J. R. E., Bleesing, J., Boesing, J., Bouso, C., Brodszki, N., Cabanillas, D., Cady, C., Callahan, M. A., Caorsi, R., Carbone, J., Carrabba, M., Castagnoli, […]
- Birth outcomes in relation to neighborhood food access and individual food insecurity during pregnancy in the Environmental Influences on Child Health Outcomes (ECHO)-wide cohort studyprogram collaborators for Environmental Influences on Child Health Outcomes, ECHO components—Coordinating Center, Data Analysis Center, Person-Reported Outcomes Core & ECHO Awardees and Cohorts, May 2024, In: American Journal of Clinical Nutrition. 119, 5, p. 1216-1226 11 p.Research output: Contribution to journal › Article › peer-review
- A novel approach to reducing hepatotoxicity related to fungal prophylaxis in pediatric lung transplant recipientsPatz-Sobczak, C., Young, J., Bunton, D., Kuklinski, C. & Estabrook, M., May 2024, In: Pediatric transplantation. 28, 3, e14740.Research output: Contribution to journal › Article › peer-review
- Laxatives for a Cold?McPhie, J. & Rivera-Spoljaric, K., May 2024, In: Journal of general internal medicine. 39, 7, p. 1087 1 p.Research output: Contribution to journal › Editorial
- Azithromycin therapy in infants hospitalized for respiratory syncytial virus bronchiolitis: Airway matrix metalloproteinase-9 levels and subsequent recurrent wheezeBeigelman, A., Goss, C. W., Wang, J., Srinivasan, M., Boomer, J., Zhou, Y., Bram, S., Casper, T. J., Coverstone, A. M., Kanchongkittiphon, W., Kuklinski, C., Storch, G. A., Schechtman, K. B., Castro, M. & Bacharier, L. B., May 2024, In: Annals of Allergy, Asthma and Immunology. 132, 5, p. 623-629 7 p.Research output: Contribution to journal › Article › peer-review
- Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubulesGenomics England Research Consortium, Apr 26 2024, In: Science. 384, 6694, eadf5489.Research output: Contribution to journal › Article › peer-review
- Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesiaGaston, B., Smith, L. A., Davis, M. D., Saunders, J., Daniels, I., Horani, A., Brody, S. L., Giddings, O., Zhao, Y. & Marozkina, N., Apr 2024, In: American Journal of Physiology – Lung Cellular and Molecular Physiology. 326, 4, p. L468-L476Research output: Contribution to journal › Article › peer-review