Explore our research fingerprint
Jump over to the division’s research profile to fully explore the nature and scope of our research publications over the years.
Our labs
Horani Lab
Amjad Horani, MD
The Horani lab research focuses on airway epithelial cell differentiation and regulation with special interest in cilia assembly and how it relates to impaired mucociliary clearance and the biology of primary ciliary dyskinesia. The lab uses primary culture of human and mouse cells and employs genetic manipulation methods to investigate the function of novel proteins involved in ciliogenesis.
Rubenstein Lab
Ronald Rubenstein, MD, PhD
The Rubenstein lab focuses on the mechanisms by which small molecules may improve the function of mutant proteins that cause disease due to abnormal biogenesis and trafficking. These studies initially focused on epithelial ion channels relevant to Cystic Fibrosis, and have expanded to address fundamental biologic questions related to the regulation of protein biogenesis and trafficking in a number of other diseases and conditions.
Recent publications
- Safety of non-cuffed tunneled central venous catheters in adults with cystic fibrosisDehbozorgi, A., Jandali, B., Turner, R., Rohr, A., Custer, B., Young, K., Walter, C., Clark, L., Li, Y., Polineni, D. & Mermis, J., Jun 2024, In: Respiratory Medicine and Research. 85, 101073.Research output: Contribution to journal › Article › peer-review
- Azithromycin therapy in infants hospitalized for respiratory syncytial virus bronchiolitis: Airway matrix metalloproteinase-9 levels and subsequent recurrent wheezeBeigelman, A., Goss, C. W., Wang, J., Srinivasan, M., Boomer, J., Zhou, Y., Bram, S., Casper, T. J., Coverstone, A. M., Kanchongkittiphon, W., Kuklinski, C., Storch, G. A., Schechtman, K. B., Castro, M. & Bacharier, L. B., May 2024, In: Annals of Allergy, Asthma and Immunology. 132, 5, p. 623-629 7 p.Research output: Contribution to journal › Article › peer-review
- Improvements in Sleep After Shoulder Arthroscopy Are Correlated With Improvements in Various Patient-Reported Outcomes: A Systematic ReviewTeytelbaum, D., Wegenka, L., Wolk, R., Ali, A., Kaar, C. R. J. & Karr, S., Apr 2024, In: Arthroscopy, Sports Medicine, and Rehabilitation. 6, 2, 100883.Research output: Contribution to journal › Review article › peer-review
- Gilbert's syndrome leads to elevated bilirubin after initiation of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosisPatel, N., Ansar, M., Pham, A., Thomsen, K., McKinzie, C. J., Polineni, D., Esther, C. R. & Brown, R. F., Apr 2024, In: Pediatric Pulmonology. 59, 4, p. 863-866 4 p.Research output: Contribution to journal › Article › peer-review
- Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesiaGaston, B., Smith, L. A., Davis, M. D., Saunders, J., Daniels, I., Horani, A., Brody, S. L., Giddings, O., Zhao, Y. & Marozkina, N., Apr 1 2024, In: American Journal of Physiology – Lung Cellular and Molecular Physiology. 326, 4, p. L468-L476Research output: Contribution to journal › Article › peer-review
- Incorporating a Three-Dimensional Printed Airway into a Pediatric Flexible Bronchoscopy CurriculumPainter, N., Monovoukas, D., Delecaris, A. O., Coverstone, A. M., Zopf, D. A. & Saba, T. G., Mar 2024, In: ATS Scholar. 5, 1, p. 142-153 12 p.Research output: Contribution to journal › Article › peer-review
- Gene-based association study of rare variants in children of diverse ancestries implicates TNFRSF21 in the development of allergic asthmaClay, S., Alladina, J., Smith, N. P., Visness, C. M., Wood, R. A., O'Connor, G. T., Cohen, R. T., Khurana Hershey, G. K., Kercsmar, C. M., Gruchalla, R. S., Gill, M. A., Liu, A. H., Kim, H., Kattan, M., Bacharier, L. B., Rastogi, D., Rivera-Spoljaric, K., Robison, R. G., Gergen, P. J., Busse, W. W., & 7 othersVillani, A. C., Cho, J. L., Medoff, B. D., Gern, J. E., Jackson, D. J., Ober, C. & Dapas, M., Mar 2024, In: Journal of […]
- Clinical Observations in Patients With Cystic Fibrosis-Related Diabetes and Self-Reported Ototoxicity SymptomsNichols, N., Rubenstein, R. C., Kelly, A., Vachhani, J. J., Echaluse, M. V. & Garinis, A. C., Mar 2024, In: American Journal of Audiology. 33, 1, p. 283-291 9 p.Research output: Contribution to journal › Article › peer-review
- Immunoglobulin replacement products protect against SARS-CoV-2 infection in vivo despite poor neutralizing activityZimmerman, O., Altman Doss, A. M., Ying, B., Liang, C. Y., Mackin, S. R., Davis-Adams, H. G., Adams, L. J., VanBlargan, L. A., Chen, R. E., Scheaffer, S. M., Desai, P., Raju, S., Mantia, T. L., O’Shaughnessy, C. C., Monroy, J. M., James Wedner, H., Rigell, C. J., Kau, A. L., Dy, T. B., Ren, Z., & 7 othersTurner, J. S., O’Halloran, J. A., Presti, R. M., Kendall, P. L., Fremont, D. H., Ellebedy, A. H. & Diamond, M. S., Feb 8 2024, In: JCI Insight. 9, 3, […]
- Prenatal vitamin D supplementation to prevent childhood asthma: 15-year results from the Vitamin D Antenatal Asthma Reduction Trial (VDAART)Weiss, S. T., Mirzakhani, H., Carey, V. J., O'Connor, G. T., Zeiger, R. S., Bacharier, L. B., Stokes, J. & Litonjua, A. A., Feb 2024, In: Journal of Allergy and Clinical Immunology. 153, 2, p. 378-388 11 p.Research output: Contribution to journal › Review article › peer-review