Research

Explore our research fingerprint

Jump over to the division’s research profile to fully explore the nature and scope of our research publications over the years.

Complete research profile

Our labs

Gill Lab

Michelle Gill, MD, PhD

Research profile

Horani Lab

Amjad Horani, MD

The Horani lab research focuses on airway epithelial cell differentiation and regulation with special interest in cilia assembly and how it relates to impaired mucociliary clearance and the biology of primary ciliary dyskinesia. The lab uses primary culture of human and mouse cells and employs genetic manipulation methods to investigate the function of novel proteins involved in ciliogenesis.

Research profile

Polineni Lab

Deepika Polineni, MD, MPH

Research profile

Rubenstein Lab

Ronald Rubenstein, MD, PhD

The Rubenstein lab focuses on the mechanisms by which small molecules may improve the function of mutant proteins that cause disease due to abnormal biogenesis and trafficking. These studies initially focused on epithelial ion channels relevant to Cystic Fibrosis, and have expanded to address fundamental biologic questions related to the regulation of protein biogenesis and trafficking in a number of other diseases and conditions.

Research profile

Recent publications

  • Host factors are associated with vaginal microbiome structure in pregnancy in the ECHO Cohort Consortium
    Host factors are associated with vaginal microbiome structure in pregnancy in the ECHO Cohort ConsortiumMcKee, K., Bassis, C. M., Golob, J., Palazzolo, B., Sen, A., Comstock, S. S., Rosas-Salazar, C., Stanford, J. B., O’Connor, T., Gern, J. E., Paneth, N., Dunlop, A. L., Smith, P. B., Newby, L. K., Adair, L., Jacobson, L. P., Catellier, D., McGrath, M., Douglas, C. & Duggal, P. & 271 others, Knapp, E., Kress, A., Blackwell, C. K., Mansolf, M. A., Lai, J. S., Ho, E., Cella, D., Gershon, R., Macy, M. L., Das, S. R., Freedman, J. E., Mallal, S. A., McLean, J. A., […]
  • Race and Ethnicity, Gender, and Promotion of Physicians in Academic Medicine
    Race and Ethnicity, Gender, and Promotion of Physicians in Academic MedicineClark, L., Shergina, E., Machado, N., Scheuermann, T. S., Sultana, N., Polineni, D., Shih, G. H., Simari, R. D., Wick, J. A. & Richter, K. P., Nov 4 2024, In: JAMA Network Open. 7, 11, p. e2446018Research output: Contribution to journal › Article › peer-review
  • Race, Gender, and Faculty Retention in Academic Medicine
    Race, Gender, and Faculty Retention in Academic MedicineScheuermann, T. S., Clark, L., Sultana, N., Machado, N., Shergina, E., Polineni, D., Shih, G. H., Simari, R. D., Wick, J. A. & Richter, K. P., Nov 4 2024, In: JAMA Network Open. 7, 11, p. e2445143Research output: Contribution to journal › Article › peer-review
  • Ultrastructure expansion microscopy (U-ExM) of mouse and human kidneys for analysis of subcellular structures
    Ultrastructure expansion microscopy (U-ExM) of mouse and human kidneys for analysis of subcellular structuresLangner, E., Puapatanakul, P., Pudlowski, R., Alsabbagh, D. Y., Miner, J. H., Horani, A., Dutcher, S. K., Brody, S. L., Wang, J. T., Suleiman, H. Y. & Mahjoub, M. R., Nov 2024, In: Cytoskeleton. 81, 11, p. 618-638 21 p.Research output: Contribution to journal › Article › peer-review
  • Home and school pollutant exposure, respiratory outcomes, and influence of historical redlining
    Home and school pollutant exposure, respiratory outcomes, and influence of historical redliningJung, K. H., Argenio, K. L., Jackson, D. J., Miller, R. L., Perzanowski, M. S., Rundle, A. G., Bacharier, L. B., Busse, W. W., Cohen, R. T., Visness, C. M., Gill, M. A., Gruchalla, R. S., Hershey, G. K., Kado, R. K., Sherenian, M. G., Liu, A. H., Makhija, M. M., Pillai, D. K., Rivera-Spoljaric, K. & Gergen, P. J. & 5 others, Altman, M. C., Sandel, M. T., Sorkness, C. A., Kattan, M. & Lovinsky-Desir, S., Nov 2024, In: Journal of Allergy and Clinical Immunology. 154, 5, p. […]
  • Factors Associated with Non-Completion of a Pediatric Metabolic and Bariatric Surgery Program
    Factors Associated with Non-Completion of a Pediatric Metabolic and Bariatric Surgery ProgramPhelps, H. M., Shelton, M., Nicol, G. E., Stoll, J., Sumski, C. A., Kaar, C. R. J., Eagon, J. C., Dimou, F., Eckhouse, S., Sprague, J. E. & Shakhsheer, B., Oct 2024, In: Journal of Pediatric Surgery. 59, 10, 161582.Research output: Contribution to journal › Article › peer-review
  • Transcriptional analysis of primary ciliary dyskinesia airway cells reveals a dedicated cilia glutathione pathway
    Transcriptional analysis of primary ciliary dyskinesia airway cells reveals a dedicated cilia glutathione pathwayKoenitzer, J. R., Gupta, D. K., Twan, W. K., Xu, H., Hadas, N., Hawkins, F. J., Beermann, M. L., Penny, G. M., Wamsley, N. T., Berical, A., Major, M. B., Dutcher, S. K., Brody, S. L. & Horani, A., Sep 10 2024, In: JCI Insight. 9, 17, e180198.Research output: Contribution to journal › Article › peer-review
  • A pediatric randomized, controlled trial of German cockroach subcutaneous immunotherapy
    A pediatric randomized, controlled trial of German cockroach subcutaneous immunotherapyInner-City Asthma and Childhood Asthma in Urban Settings Consortia, Zoratti, E., Wood, R., Pomés, A., Da Silva Antunes, R., Altman, M. C., Benson, B., Wheatley, L. M., Cho, K., Calatroni, A., Little, F. F., Pongracic, J., Makhija, M., Khurana Hershey, G. K., Sherenian, M. G., Rivera-Spoljaric, K., Stokes, J. R., Gill, M. A., Gruchalla, R. S. & Chambliss, J. & 14 others, Liu, A. H., Kattan, M., Busse, P. J., Bacharier, L. B., Sheehan, W., Kim, H., Glesner, J., Gergen, P. J., Togias, A., Baucom, J. L., Visness, C. M., Sette, […]
  • Interstitial lung disease as an indication for pediatric lung transplant
    Interstitial lung disease as an indication for pediatric lung transplantKuklinski, C. A. & Blatter, J. A., Sep 2024, In: Pediatric Pulmonology. 59, 9, p. 2313-2320 8 p.Research output: Contribution to journal › Review article › peer-review
  • Not all are the same: the power of registries in defining genotype–phenotype relationships in primary ciliary dyskinesia
    Not all are the same: the power of registries in defining genotype–phenotype relationships in primary ciliary dyskinesiaHorani, A. & Mill, P., Aug 1 2024, In: European Respiratory Journal. 64, 2, 2401026.Research output: Contribution to journal › Editorial